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David Sinclair is a professor of genetics at Harvard University, he is the world's leading longevity researcher. TIME magazine has named him one of the 100 most influential people in the world.He is a long-term user of NMN. David Sinclair's research team is a world leader in understanding the causes of aging and reversing its direction.In his studies, David Sinclair is focused in the molecules that affect aging.
One of the most significant molecules he focuses on is nicotinamide mononucleotide (NMN). In the body, NMN is converted to natural NAD +, a component that allows sirtuins and other DNA repair molecules to function.
NMN helps maintain and repair damaged DNA and epigenome. The epigenome plays a very important role in aging. As we get older, more and more the epigenome becomes unregulated. The unregulated epigenome causes problems in the cell regeneration and leads to its impaired function.
Research have shown impressive results with NMN, in prevention of aging and supporting healthy cell regeneration.
In experiments on mice the group of researchers led by David Sinclair, the effects of NMN were stuning. Significantly more endurance and improved metabolism were observed in older mice with NMN. Related to human age the mice of 60 years old who received NMN were in better physical condition than mice in the age of 20 years without NMN.
These mice were born on the same day. Their relative age is 60 years. The one on the right has received NMN.
Decreased stem cell function is also one reason for aging.NMN can also improve stem cell health significantly as studies seem to show.
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